Enmetazobactam

Enmetazobactam
Legal status
Legal status
  • Investigational
Identifiers
  • (2S,3S,5R)-3-methyl-3-[(3-methyltriazol-3-ium-1-yl)methyl]-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC11H14F2N4O5S
Molar mass352.31 g·mol−1
3D model (JSmol)
  • C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])CN3C=C[N+](=N3)C
  • InChI=1S/C11H14N4O5S/c1-11(6-14-4-3-13(2)12-14)9(10(17)18)15-7(16)5-8(15)21(11,19)20/h3-4,8-9H,5-6H2,1-2H3/t8-,9+,11+/m1/s1
  • Key:HFZITXBUTWITPT-YWVKMMECSA-N

Enmetazobactam (AAI-101) is an antibiotic adjuvant drug which acts as a beta-lactamase inhibitor, preventing the breakdown of other antibiotic drugs.[1]

See also

References

  1. ^ Lanier C, Melton T, Covert K (September 2024). "Cefepime-Enmetazobactam: A Drug Review of a Novel Beta-Lactam/Beta-Lactamase Inhibitor". The Annals of Pharmacotherapy: 10600280241279904. doi:10.1177/10600280241279904. PMID 39329253.
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